What is PROFHILO?

Profhilo is the first BDDE-free stabilised injectable hyaluronic acid (HA) based product for treating skin laxity.

With one of the highest concentrations of HA on the market (64mg / 2ml) it is not only boosting and hydrating the skin, but also remodels the ageing and sagging tissue.

Profhilo delivers great results as a treatment on its own or in combination with other aesthetics treatments currently on offer.

What are the benefits?

Profhilo can help to improve skin tone, texture, hydration and overall radiance.  It can help to increase firmness and elasticity and promote healthier and softer looking, and feeling, skin. Any body area can be treated with Profhilo – from the crepey skin on your knees to your upper arms, décolletage and face.

Why should I have this treatment?

As we age and the production of the ‘scaffolding’ proteins of collagen and elastin within our skin starts to reduce, many people find that skin becomes lax and wrinkles appear more visible. The overall texture of our skin is also negatively affected by the physical ageing process, with many people complaining that their skin appears dull, dry and lacklustre.

Profhilo is designed to tackle these problems through effective skin bio-remodelling, and was awarded the Aesthetics Award for Product Innovation of the Year 2016 thanks to it’s revolutionary composition without chemical cross linking agents (BDDE) and as one of the most concentrated formulations of Hyaluronic Acid on the market.

HOW DOES PROFHILO WORK

As a stabilised product Profhilo lasts in the skin around 28 days. During this time the stimulation of 4 different types of collagen and elastin takes place by slow release of HA.

The stimulation results in significant tissue improvement. Therefore we cannot say that Profhilo is a skin booster as it also has a significant tightening / lifting effect on the tissue.

UNIQUE PRODUCT

There are many characteristics that make Profhilo unique from anything else available on the market right now. There is no BDDE content. It is thermally cross-linked generating stabilised hybrid co-operative complexes of H-HA and L-HA. Despite its high HA content, it has a low inflammatory profile coupled with pro-healing properties backed by clinical studies. To fully understand this new concept in anti-ageing medicine we have to take a look at the technology first.

ADVANTAGES

In Profhilo, L-HA is released slowly from the HA hybrid complexes and therefore does not trigger the first inflammatory cytokines making it very biocompatible. It also increas¬es patient comfort during and after treatment and provides hydration to the skin especially in the epidermis – the Hydro effect.

H-HA in Profhilo provides a stable HA architecture in the dermis. This gives a volumetric effect – the Lift effect.

Another advantage of the stable co-operative hybrid complex when compared to H-HA and L-HA is the increase in the ex¬pression levels of type I and type III collagen in fibroblast and type IV and VII collagen in keratinocytes.

This results in improved skin quality and skin hydration both in the dermis and epidermis. There is also increased production of endogenous HA and elastin giving the skin a more youthful look.

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HIGHEST CONCENTRATION ON THE MARKET

Profhilo contains 32mg of low molecular weight HA (80-100Kda) and 32 mg of high molecular weight HA (1100-1400Kda). This gives one of the highest concentration of HA on the market totalling 64 mg of HA in a 2ml prefilled syringe. Remarkably this can still be extruded using a 29g needle.